pathophysiology

PATHOPHYSIOLOGY

1.wrote a note on the morphology of cell injury.

2.write aboyt the basic principles of wound healing in the skin.

3.what are the reasons for peptic ulcer?

4.what are the reasons for peptic ulcer?

5 give a brief note on chronic obstructive airways disease.

6.what are the causes of hypertension.

7.define osteoporosis.

8.give short notes in rhematoid arthritis.

9.write about the symptoms of leprosy.

10.what os syphilis.

11.give a brief account on the following.

(a)Electrolyte imbalance.

(b)pathophysiology of atherosclerosis.

12.discuss the symptoms, etiology and pathogenesis of

(a)tuberculosis

(b)Alzheimer's disease

13.discuss about pathosenecity, treatment and prevention of AIDS.

14.write about following

(a)atropy.

(b)hypertrophy

15.give short notes on meningitis

Comments

(4)2.pore transport/mechanism of drug transport

2.pore transport - It is also called as convective transport, bulk flow or filtration. -the process is important in the absorption of low molecular weight (less than 100). -low molecular size (small than the diameter of the pare) generally water-soluble drugs through marrow, aqueous filled channels or pores, in the membrane structure .ex :Urea, H₂o & Sugars.... * Chain-like.. or linear compounds of molecular weight upto 400 daltons can be absorbed by filtration. * The driving force is constituted by the hydrostatic pressure/ the asmotic differences across the membrane due to which bulk flow of water along with solid molecules occurs through, aqueous such channels →water flux that promotes such a transport is called as solvent drug. -drug permeation through water filled channels or of particular importance in renal excretion,removal of drug from the cerebrospinal fluid and entry of drugs into the liver. Note:next topic will be continued I next blog

Pharmaceutics_1 question paper

Pharmaceutics-1

(4).3.carrier mediated transport/mechanism of drug absorption/biopharmaceutics

3.carrier mediated transport - the presence of specialised transport mechanisms without which many essential water-soluble nutrients like monosacharrides ,aminoacids and vitamins will be poorly absorbed. --the mechanism is thought to involve a component of the membrane called as the carrier. --the carrier,that binds reversible or non covalent with the solute molecules to be transported. --this carrier-solute complex transverse across the membrane to the other side where it dissociated & discharges the solute molecule--the carrier then returns to its original site to complete the cycle by accepting a fresh molecule of solute . --the carrier may be an enzyme or some other component of the membrane. --the important characteristics of carrier mediated transport are; 1.the transport process is structure specific(I.e. the carriers have affinity for and transfer a drug of specific chemical structure only ;generally the carriers have special affinity for essential nutrient...

It's all about B.pharm

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